Behavioral and Neurochemical Alterations Following Thiamine Deficiency in Rodents: Relationship to Functions of Cholinergic Neurons
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چکیده
منابع مشابه
Behavioral and neurochemical alterations following thiamine deficiency in rodents: relationship to functions of cholinergic neurons.
Memory deficits are induced during the late stage (20-25 days) of thiamine-deficient (TD) feeding. In this review, the role of cholinergic neurons on the memory deficit induced by TD feeding are summarized. Although memory deficit cannot be suppressed by an injection of thiamine once it appears, such impairment was found to be protected by early treatment with thiamine during TD feeding. Admini...
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Nutritional deficiency can cause, mainly in chronic alcoholic subjects, the Wernicke encephalopathy and its chronic neurological sequela, the Wernicke-Korsakoff syndrome (WKS). Long-term chronic ethanol abuse results in hippocampal and cortical cell loss. Thiamine deficiency also alters principally hippocampal- and frontal cortical-dependent neurochemistry; moreover in WKS patients, important p...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2005
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.125.549